Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27762534 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TP53POLBSLC7A5KMT2A | |
| SCHEMBL20543766 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TP53POLBSLC7A5KMT2A | |
| SCHEMBL19699296 | 0.88 | SLC7A5 (0.54) | ALDH1A1TP53POLBSLC7A5IDO1 | |
| SCHEMBL28637433 | 0.88 | SLC7A5 (0.54) | ALDH1A1TP53POLBSLC7A5IDO1 | |
| SCHEMBL6218675 | 0.88 | SLC7A5 (0.54) | ALDH1A1TP53POLBSLC7A5IDO1 | |
| SCHEMBL13588335 | 0.87 | POLB (0.60) | ALDH1A1TP53POLBSLC7A5IDO1 | |
| SCHEMBL13535116 | 0.87 | POLB (0.60) | ALDH1A1TP53POLBSLC7A5IDO1 | |
| SCHEMBL2038370 | 0.86 | GRIA2 (0.55) | SLC7A5NOS3NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL32677180 | 0.86 | SLC7A5 (0.52) | ALDH1A1TP53POLBSLC7A5IDO1 | |
| Hydrochloric Acid SCHEMBL32676955 | 0.86 | SLC7A5 (0.52) | ALDH1A1TP53POLBSLC7A5IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10669242-B2 | Clostridium difficile toxin inhibitors | Venenum Biodesign, LLC (US) | 2020-06-02 | — | — | US | disclosed |
| US-20190194147-A1 | Novel Clostridium Difficile Toxin Inhibitors | Venenum Biodesign, LLC (US) | 2019-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190194147-A1 | Novel Clostridium Difficile Toxin Inhibitors | GABRA5, GABRA1, GABRA4 | ALDH1A1 2381/4885TP53 4810/4885POLB 4138/4885 |
| US-10669242-B2 | Clostridium difficile toxin inhibitors | GABRA5, GABRA1, GABBR2 | ALDH1A1 1908/4885TP53 4770/4885POLB 3866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.