Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | APP | P05067 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 4/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28637635 | 1.00 | L3MBTL1 (0.55) | L3MBTL1TDP1KDM4EKMT2AALDH1A1 | |
| SCHEMBL28638006 | 0.86 | TDP1 (0.62) | L3MBTL1TDP1KDM4EKMT2AALDH1A1 | |
| SCHEMBL28638005 | 0.86 | TDP1 (0.62) | L3MBTL1TDP1KDM4EKMT2AALDH1A1 | |
| SCHEMBL28652743 | 0.83 | KDM4E (0.62) | L3MBTL1TDP1KDM4EKMT2AALDH1A1 | |
| SCHEMBL28635282 | 0.82 | TDP1 (0.61) | L3MBTL1TDP1KDM4EKMT2AALDH1A1 | |
| SCHEMBL28638109 | 0.80 | GPR183 (0.66) | L3MBTL1TDP1KDM4EKMT2AALDH1A1 | |
| SCHEMBL9567242 | 0.80 | APP (0.57) | L3MBTL1TDP1KDM4EKMT2AALDH1A1 | |
| SCHEMBL9567245 | 0.80 | APP (0.57) | L3MBTL1TDP1KDM4EKMT2AALDH1A1 | |
| SCHEMBL28647986 | 0.80 | ACHE (0.76) | TDP1ACHE | |
| SCHEMBL9567116 | 0.79 | APP (0.56) | L3MBTL1TDP1KDM4EKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461639-B | Piperazine-containing ferulic acid derivative, and preparation method and application thereof | 贵州大学 | 2022-11-01 | — | — | CN | disclosed |
| CN-113461639-A | Piperazine-containing ferulic acid derivative, and preparation method and application thereof | 贵州大学 | 2021-10-01 | — | — | CN | disclosed |