SCHEMBL28637697

SCHEMBL28637697

ClC(=CBr)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
ALDH1A1 P00352 3/20 0.38
CES2 O00748 2/20 0.38
CES1 P23141 2/20 0.38
DAO P14920 1/20 0.38
TSHR P16473 1/20 0.38
NAPRT Q6XQN6 1/20 0.38
MAPK1 P28482 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
PLAU P00749 1/20 0.36
GSK3B P49841 2/20 0.36
TRPA1 O75762 1/20 0.36
HIF1A Q16665 1/20 0.36
AKT1 P31749 1/20 0.36
PTPN1 P18031 1/20 0.36
F2 P00734 1/20 0.35
F10 P00742 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28858450 1.00 MEN1 (0.44) MEN1KMT2ASMN1; SMN2NPSR1ALDH1A1
SCHEMBL28858458 0.81 CES1 (0.46) MEN1KMT2ASMN1; SMN2NPSR1ALDH1A1
SCHEMBL28858456 0.81 CES1 (0.46) MEN1KMT2ASMN1; SMN2NPSR1ALDH1A1
SCHEMBL8921796 0.76 MEN1 (0.45) MEN1KMT2ASMN1; SMN2NPSR1ALDH1A1
SCHEMBL10995634 0.76 MEN1 (0.45) MEN1KMT2ASMN1; SMN2NPSR1ALDH1A1
SCHEMBL5639403 0.76 MEN1 (0.50) MEN1KMT2ASMN1; SMN2NPSR1ALDH1A1
SCHEMBL5639401 0.76 MEN1 (0.50) MEN1KMT2ASMN1; SMN2NPSR1ALDH1A1
SCHEMBL8565313 0.76 MEN1 (0.50) MEN1KMT2ASMN1; SMN2NPSR1ALDH1A1
SCHEMBL7175389 0.76 MEN1 (0.45) MEN1KMT2ASMN1; SMN2NPSR1ALDH1A1
SCHEMBL11602973 0.74 MEN1 (0.44) MEN1KMT2ASMN1; SMN2NPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115197046-B Halogenation method of unsaturated hydrocarbon 华南理工大学 2023-12-15 CN disclosed
CN-115197046-A Halogenation method of unsaturated hydrocarbon 华南理工大学 2022-10-18 CN disclosed
CN-109400440-B Halogenated conjugated 1, 3-eneyne compound and preparation method and application thereof 浙江工业大学 2021-10-15 CN disclosed