SCHEMBL5639403

SCHEMBL5639403

CC=C(Cl)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
SMN1; SMN2 Q16637 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
ALDH1A1 P00352 5/20 0.40
HIF1A Q16665 2/20 0.40
CES2 O00748 3/20 0.39
CES1 P23141 3/20 0.39
TSHR P16473 2/20 0.39
DAO P14920 1/20 0.39
NAPRT Q6XQN6 1/20 0.39
MAPK1 P28482 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
KDM1A O60341 1/20 0.38
ESR1 P03372 1/20 0.37
TRPA1 O75762 1/20 0.37
GSK3B P49841 1/20 0.37
AKT1 P31749 1/20 0.37
MAPT P10636 1/20 0.37
PLAU P00749 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8565313 1.00 MEN1 (0.50) MEN1KMT2ASMN1; SMN2NPSR1ALDH1A1
SCHEMBL5639401 1.00 MEN1 (0.50) MEN1KMT2ASMN1; SMN2NPSR1ALDH1A1
SCHEMBL15047755 0.81 ATM (0.37) MEN1KMT2ASMN1; SMN2NPSR1ALDH1A1
SCHEMBL28858458 0.78 CES1 (0.46) MEN1KMT2ASMN1; SMN2NPSR1ALDH1A1
SCHEMBL10995634 0.78 MEN1 (0.45) MEN1KMT2ASMN1; SMN2NPSR1ALDH1A1
SCHEMBL28858456 0.78 CES1 (0.46) MEN1KMT2ASMN1; SMN2NPSR1ALDH1A1
SCHEMBL7175389 0.78 MEN1 (0.45) MEN1KMT2ASMN1; SMN2NPSR1ALDH1A1
SCHEMBL8921796 0.78 MEN1 (0.45) MEN1KMT2ASMN1; SMN2NPSR1ALDH1A1
SCHEMBL11518035 0.77 L3MBTL1 (0.67) MEN1KMT2ASMN1; SMN2ALDH1A1HIF1A
SCHEMBL3852047 0.76 MEN1 (0.44) MEN1KMT2ASMN1; SMN2NPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0643781-B1 ELECTROCATALYTIC ASYMMETRIC DIHYDROXYLATION OF OLEFINIC COMPOUNDS SEPRACOR INC (US) 1998-06-24 EP claimed
US-5419817-A Osmium tetroxide catalyst; preparing hydroxycarbonyl compounds from enol ether or vinyl halide SEPRACOR INC. (US) 1995-05-30 US claimed
EP-0643781-A1 ELECTROCATALYTIC ASYMMETRIC DIHYDROXYLATION OF OLEFINIC COMPOUNDS SEPRACOR, INC. (US) 1995-03-22 EP claimed
WO-1993017150-A1 ELECTROCATALYTIC ASYMMETRIC DIHYDROXYLATION OF OLEFINIC COMPOUNDS SEPRACOR, INC. (US) 1993-09-02 WO claimed
US-4795576-A EXTREME PRESSURE, NONCORROSIVE INSTITUT FRANCAIS DU PETROLE (FR) 1989-01-03 US claimed
EP-3527593-B1 ISOCYANATE COMPOSITION, METHOD FOR PRODUCING ISOCYANATE COMPOSITION, AND METHOD FOR PRODUCING ISOCYANATE POLYMER ASAHI CHEMICAL IND (JP) 2025-07-23 EP disclosed
EP-3527600-B1 ISOCYANATE COMPOSITION AND PRODUCTION METHOD FOR ISOCYANATE POLYMER ASAHI CHEMICAL IND (JP) 2025-07-09 EP disclosed
US-20230130823-A1 PROCESS FOR THE PRODUCTION OF ANTITUMOUR PHARMACEUTICAL COMPOSITIONS USING PUSH-PULL BUTADIENES, COMPOUNDS AND USES THEREOF ANHANGUERA EDUCACIONAL PARTICIPAÇÕES S/A (BR) 2023-04-27 US disclosed
CN-112979917-B Isocyanate composition, method for producing isocyanate composition, and method for producing isocyanate polymer 旭化成株式会社 2023-04-25 CN disclosed
US-20230114799-A1 ISOCYANATE COMPOSITION AND METHOD FOR PRODUCING ISOCYANATE POLYMER ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-04-13 US disclosed
US-11548975-B2 Isocyanate composition and method for producing isocyanate polymer ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-01-10 US disclosed
EP-3536683-B1 POLYISOCYANATE COMPOSITION AND ISOCYANATE POLYMER COMPOSITION ASAHI CHEMICAL IND (JP) 2021-11-24 EP disclosed
WO-1993017150-A1 ELECTROCATALYTIC ASYMMETRIC DIHYDROXYLATION OF OLEFINIC COMPOUNDS SEPRACOR, INC. (US) 1993-09-02 WO disclosed
US-RE33125-E HYPOTENSIVE AGENTS RORER PHARMACEUTICAL CORPORATION (US) 1989-12-05 US disclosed
US-4460585-A HYPOTENSIVE AGENTS WILLIAM H. RORER, INC. (US) 1984-07-17 US disclosed
US-4076537-A Light-sensitive materials containing organo tellurium or selenium compounds and sensitizers FUJI PHOTO FILM CO., LTD. (JA) 1978-02-28 US disclosed
US-4076530-A Dry photographic copying method for producing Te images FUJI PHOTO FILM CO., LTD. (JA) 1978-02-28 US disclosed
US-4062685-A ORGANO-TELLURIUM COMPOUND FUJI PHOTO FILM CO., LTD. (JA) 1977-12-13 US disclosed
US-4000200-A PREPARATION OF KETONES FROM OLEFINS PETRO-TEX CHEMICAL CORPORATION (US) 1976-12-28 US disclosed
US-3953409-A ALFIN CATALYST, MOLECULAR WEIGHT REGULATOR JAPAN SYNTHETIC RUBBER CO., LTD. (JA) 1976-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11548975-B2 Isocyanate composition and method for producing isocyanate polymer IDH3A, IDH2, IDH3B MEN1 2333/4885KMT2A 688/4885SMN1; SMN2 3482/4885
US-20230130823-A1 PROCESS FOR THE PRODUCTION OF ANTITUMOUR PHARMACEUTICAL COMPOSITIONS USING PUSH-PULL BUTADIENES, COMPOUNDS AND USES THEREOF BAD, BAX, PDCD4 MEN1 2628/4885KMT2A 4589/4885SMN1; SMN2 3703/4885
US-20230114799-A1 ISOCYANATE COMPOSITION AND METHOD FOR PRODUCING ISOCYANATE POLYMER IDH3A, IDH2, IDH3B MEN1 2041/4885KMT2A 632/4885SMN1; SMN2 3286/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.