SCHEMBL7175389

SCHEMBL7175389

OC=C(Cl)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
ALDH1A1 P00352 3/20 0.39
CES2 O00748 2/20 0.39
CES1 P23141 2/20 0.39
TSHR P16473 2/20 0.39
DAO P14920 1/20 0.39
NAPRT Q6XQN6 1/20 0.39
MAPK1 P28482 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
TRPA1 O75762 1/20 0.37
GSK3B P49841 1/20 0.37
HIF1A Q16665 1/20 0.37
AKT1 P31749 1/20 0.37
PLAU P00749 1/20 0.37
F2 P00734 1/20 0.36
F10 P00742 1/20 0.36
F12 P00748 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5639401 0.78 MEN1 (0.50) MEN1KMT2ASMN1; SMN2NPSR1ALDH1A1
SCHEMBL28858458 0.78 CES1 (0.46) MEN1KMT2ASMN1; SMN2NPSR1ALDH1A1
SCHEMBL10995634 0.78 MEN1 (0.45) MEN1KMT2ASMN1; SMN2NPSR1ALDH1A1
SCHEMBL8921796 0.78 MEN1 (0.45) MEN1KMT2ASMN1; SMN2NPSR1ALDH1A1
SCHEMBL5639403 0.78 MEN1 (0.50) MEN1KMT2ASMN1; SMN2NPSR1ALDH1A1
SCHEMBL28858456 0.78 CES1 (0.46) MEN1KMT2ASMN1; SMN2NPSR1ALDH1A1
SCHEMBL8565313 0.78 MEN1 (0.50) MEN1KMT2ASMN1; SMN2NPSR1ALDH1A1
SCHEMBL28637697 0.76 MEN1 (0.44) MEN1KMT2ASMN1; SMN2NPSR1ALDH1A1
SCHEMBL3852047 0.76 MEN1 (0.44) MEN1KMT2ASMN1; SMN2NPSR1ALDH1A1
SCHEMBL28858450 0.76 MEN1 (0.44) MEN1KMT2ASMN1; SMN2NPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6576400-B1 Acrylic ester polymer TORAY INDUSTRIES, INC. (JP) 2003-06-10 US disclosed
EP-1031880-A1 POSITIVE RADIATION-SENSITIVE COMPOSITION TORAY INDUSTRIES, INC. (JP) 2000-08-30 EP disclosed