Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.45 |
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699018 | 0.85 | PDE10A (0.49) | PDE10ATDP1L3MBTL1KDM4EPKM | |
| Hydrochloric Acid SCHEMBL9989517 | 0.83 | PDE10A (0.48) | PDE10ATDP1L3MBTL1KDM4EPKM | |
| SCHEMBL28079387 | 0.82 | L3MBTL1 (0.58) | PDE10ATDP1L3MBTL1KDM4EPKM | |
| SCHEMBL5786475 | 0.78 | HTR2A (0.50) | HTR2AHTR2CKCNH2CHRM1HRH1 | |
| Hydrochloric Acid SCHEMBL5785380 | 0.77 | HTR2A (0.49) | HTR2AHTR2CKCNH2CHRM1HRH1 | |
| SCHEMBL7701524 | 0.74 | PDE10A (0.57) | PDE10ATDP1L3MBTL1KDM4EPKM | |
| SCHEMBL6396966 | 0.73 | HTR2A (0.41) | PDE10AHTR2ACHRM1HRH1OPRM1 | |
| Hydrochloric Acid SCHEMBL9988047 | 0.72 | PDE10A (0.56) | PDE10ATDP1L3MBTL1KDM4EPKM | |
| SCHEMBL12146723 | 0.72 | TDP1 (0.48) | PDE10ATDP1L3MBTL1RAF1KDM4E | |
| SCHEMBL12146715 | 0.72 | TDP1 (0.48) | PDE10ATDP1L3MBTL1RAF1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107206003-B | Systems, methods, and compositions for cross-linking treatment of the eye | 艾维德洛公司 | 2021-10-26 | — | — | CN | disclosed |