Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8923491 | 0.88 | STS (0.43) | STSPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8923498 | 0.88 | STS (0.43) | STSPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28632434 | 0.86 | STS (0.42) | STSPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30882363 | 0.79 | JAK2 (0.39) | STSGPR119JAK2JAK1 | |
| SCHEMBL194209 | 0.79 | — | — | |
| SCHEMBL387446 | 0.79 | — | — | |
| SCHEMBL28566941 | 0.79 | STS (0.38) | STSNR1H2NR1H3GPR119JAK2 | |
| SCHEMBL3547375 | 0.78 | — | — | |
| SCHEMBL2819757 | 0.78 | — | — | |
| SCHEMBL28625824 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113395996-A | Arginase inhibitors and methods of use thereof | 阿斯利康(瑞典)有限公司 | 2021-09-14 | — | — | CN | disclosed |