Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.78 |
| ▸ | TSHR | P16473 | 1/20 | 0.78 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19617048 | 0.85 | LMNA (0.76) | ALDH1A1TSHRLMNAKDM4EKMT2A | |
| SCHEMBL28641649 | 0.82 | ALDH1A1 (0.75) | ALDH1A1TSHRLMNAKDM4EKMT2A | |
| SCHEMBL28641648 | 0.82 | ALDH1A1 (0.75) | ALDH1A1TSHRLMNAKDM4EKMT2A | |
| SCHEMBL28652671 | 0.80 | ALDH1A1 (0.51) | ALDH1A1TSHRLMNAKDM4EKMT2A | |
| SCHEMBL14844548 | 0.79 | ALDH1A1 (0.69) | ALDH1A1TSHRLMNAKDM4EKMT2A | |
| SCHEMBL16047928 | 0.79 | ALDH1A1 (0.69) | ALDH1A1TSHRLMNAKDM4EKMT2A | |
| SCHEMBL14844551 | 0.79 | ALDH1A1 (0.69) | ALDH1A1TSHRLMNAKDM4EKMT2A | |
| SCHEMBL22578352 | 0.76 | ALDH1A1 (0.66) | ALDH1A1TSHRLMNAKDM4EKMT2A | |
| SCHEMBL15503855 | 0.74 | ALDH1A1 (0.63) | ALDH1A1TSHRLMNAKDM4EKMT2A | |
| SCHEMBL22639895 | 0.74 | ALDH1A1 (1.00) | ALDH1A1TSHRLMNAKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113549074-A | Triazole group-containing fused ring derivative inhibitor, and preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2021-10-26 | — | — | CN | disclosed |
| CN-113527307-A | Triazole group-containing fused ring derivative inhibitor, and preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2021-10-22 | — | — | CN | disclosed |