Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.69 |
| ▸ | F3 | P13726 | 1/20 | 0.69 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.69 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.69 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.69 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.69 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.69 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.69 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.69 |
| ▸ | TBXAS1 | P24557 | 13/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.51 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Niacinamide SCHEMBL28637516 | 0.92 | F7 (0.58) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL28768072 | 0.90 | F7 (0.79) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL11742728 | 0.89 | F7 (0.81) | F7F3SARM1SIRT2SIRT6 | |
| Stearic Acid SCHEMBL1648837 | 0.88 | TBXAS1 (0.67) | F7F3SARM1SIRT2SIRT6 | |
| Palmitic Acid SCHEMBL28061780 | 0.88 | TBXAS1 (0.67) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL28645721 | 0.88 | F7 (0.54) | F7F3SARM1SIRT2SIRT6 | |
| Niacin SCHEMBL23069545 | 0.87 | ALDH1A1 (0.70) | TBXAS1ALDH1A1APPGAAHCAR3 | |
| Niacinamide SCHEMBL17396609 | 0.87 | F7 (0.73) | F7F3SARM1SIRT2SIRT6 | |
| Azelaic Acid SCHEMBL28673360 | 0.86 | F7 (0.71) | F7F3SARM1SIRT2SIRT6 | |
| Azelaic Acid SCHEMBL5982892 | 0.86 | F7 (0.71) | F7F3SARM1SIRT2SIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115433164-B | Nicotinamide derivative, preparation method thereof and application thereof in resisting aging and prolonging life | 南京师范大学 | 2023-12-12 | — | — | CN | claimed |
| CN-115433164-A | Nicotinamide derivative, preparation method thereof and application thereof in anti-aging and life prolonging | 南京师范大学 | 2022-12-06 | — | — | CN | claimed |
| CN-115433164-B | Nicotinamide derivative, preparation method thereof and application thereof in resisting aging and prolonging life | 南京师范大学 | 2023-12-12 | — | — | CN | disclosed |
| CN-115433164-A | Nicotinamide derivative, preparation method thereof and application thereof in anti-aging and life prolonging | 南京师范大学 | 2022-12-06 | — | — | CN | disclosed |
| CN-113367243-A | Additive for protecting intestinal health of piglets | 广东省农业科学院动物科学研究所 | 2021-09-10 | — | — | CN | disclosed |