Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | BUB1 | O43683 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28652312 | 0.88 | KDM4E (0.48) | GAAKDM4EALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL21900227 | 0.87 | MAPT (0.46) | GAAKDM4EALDH1A1HTT | |
| SCHEMBL19873713 | 0.81 | GAA (0.47) | GAAALDH1A1 | |
| SCHEMBL17870725 | 0.79 | GAA (0.47) | GAAKDM4EMEN1KMT2A | |
| SCHEMBL19873897 | 0.79 | GAA (0.42) | GAAALDH1A1KMT2APABPC1 | |
| SCHEMBL28638744 | 0.78 | GNRHR (0.45) | MEN1KMT2A | |
| SCHEMBL19873831 | 0.77 | GAA (0.43) | GAAALDH1A1SMN1; SMN2KMT2APABPC1 | |
| SCHEMBL28638741 | 0.74 | GAA (0.42) | GAAKDM4EALDH1A1TP53MEN1 | |
| SCHEMBL21900257 | 0.70 | GAA (0.46) | GAAKDM4EALDH1A1CASP3KMT2A | |
| SCHEMBL14115659 | 0.65 | SMN1; SMN2 (0.47) | GAAKDM4EALDH1A1SMN1; SMN2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3708566-B1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2023-02-08 | — | — | EP | disclosed |
| CN-107428744-B | Novel heterocyclic compounds and their use in medicine and cosmetics | 盖尔德马研究及发展公司 | 2021-09-24 | — | — | CN | disclosed |