Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21900257 | 0.87 | GAA (0.46) | GAAKMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL28638669 | 0.77 | GNRHR (0.39) | GAAKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL28652312 | 0.76 | KDM4E (0.48) | GAAKMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL28639201 | 0.74 | GAA (0.40) | GAAKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL19873831 | 0.72 | GAA (0.43) | GAAKMT2AALDH1A1MAPTPABPC1 | |
| SCHEMBL21900227 | 0.68 | MAPT (0.46) | GAAALDH1A1KDM4EMAPTL3MBTL1 | |
| SCHEMBL38659645 | 0.66 | POLB (0.37) | KMT2AALDH1A1PTGS2KDM4EMAPT | |
| SCHEMBL28656630 | 0.66 | ALDH1A1 (0.35) | KMT2ACRHBPCRHR2ALDH1A1LMNA | |
| SCHEMBL28653826 | 0.66 | ALDH1A1 (0.35) | KMT2ACRHBPCRHR2ALDH1A1LMNA | |
| SCHEMBL28653825 | 0.66 | ALDH1A1 (0.35) | KMT2ACRHBPCRHR2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107428744-B | Novel heterocyclic compounds and their use in medicine and cosmetics | 盖尔德马研究及发展公司 | 2021-09-24 | — | — | CN | disclosed |