Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28639201 | 0.88 | GAA (0.40) | KDM4ESMN1; SMN2GAAALDH1A1KMT2A | |
| SCHEMBL17870725 | 0.86 | GAA (0.47) | KDM4EGAAKMT2AMEN1CYP2C9 | |
| SCHEMBL19873897 | 0.81 | GAA (0.42) | GAAALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL19873831 | 0.79 | GAA (0.43) | SMN1; SMN2GAARAB9AALDH1A1KMT2A | |
| SCHEMBL21900227 | 0.79 | MAPT (0.46) | KDM4EGAAALDH1A1MAPT | |
| SCHEMBL19873713 | 0.78 | GAA (0.47) | GAAALDH1A1LMNA | |
| SCHEMBL28649424 | 0.77 | GNRHR (0.45) | KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL28638741 | 0.76 | GAA (0.42) | KDM4EGAANPC1ALDH1A1KMT2A | |
| SCHEMBL21900257 | 0.72 | GAA (0.46) | KDM4EGAARAB9AALDH1A1KMT2A | |
| SCHEMBL30765438 | 0.68 | KDM4E (0.50) | KDM4ESMN1; SMN2GAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3708566-B1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2023-02-08 | — | — | EP | disclosed |
| CN-107428744-B | Novel heterocyclic compounds and their use in medicine and cosmetics | 盖尔德马研究及发展公司 | 2021-09-24 | — | — | CN | disclosed |