SCHEMBL2863928

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9612401	0.89	SOS1 (0.46)	SOS1DRD1DRD2DRD4DRD5
	SCHEMBL2855126	0.89	SOS1 (0.43)	SOS1CA12CA1CA2CA9
	SCHEMBL26372840	0.84	DRD1 (0.41)	CA12CA1CA2CA9HDAC8
	SCHEMBL584898	0.84	CA12 (0.53)	CA12CA1CA2CA9HDAC8
	SCHEMBL2863795	0.83	DRD1 (0.41)	CA12CA1CA2CA9HDAC8
	SCHEMBL16381756	0.82	CA12 (0.56)	CA12CA1CA2CA9HDAC8
	SCHEMBL2861982	0.82	DRD1 (0.38)	SOS1CA12CA1CA2CA9
	SCHEMBL2999442	0.81	SOS1 (0.55)	SOS1GPR84CYP2C9CYP2C19CES1
	SCHEMBL6196935	0.79	DRD1 (0.45)	CA12CA1CA2CA9HDAC8
	SCHEMBL2991961	0.76	SOS1 (0.48)	SOS1CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.