Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28641666 | 0.83 | S100A4 (0.40) | MAPTKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL6474422 | 0.80 | SMN1; SMN2 (0.48) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL28646145 | 0.78 | S100A4 (0.52) | MAPTKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL15025770 | 0.77 | SMN1; SMN2 (0.51) | MAPTKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL1777203 | 0.75 | SMN1; SMN2 (0.52) | KMT2AMEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL29840690 | 0.75 | SMN1; SMN2 (0.52) | KMT2AMEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL5441890 | 0.75 | SMN1; SMN2 (0.52) | KMT2AMEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL20678399 | 0.75 | MEN1 (0.46) | MAPTKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL6502119 | 0.74 | SMPD1 (0.52) | MAPTNPC1RAB9AL3MBTL1CYSLTR2 | |
| SCHEMBL3222619 | 0.74 | CYSLTR2 (0.50) | MAPTKMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113387779-A | Synthesis and preparation method of fluorenyl compound with 4-position substituent | 南京工业大学 | 2021-09-14 | — | — | CN | disclosed |