Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 2/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | BCL2 | P10415 | 2/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | PTPRC | P08575 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28639280 | 0.78 | MAPT (0.43) | S100A4TRPV1BCL2MCL1ALDH1A1 | |
| SCHEMBL29338964 | 0.78 | EGFR (0.55) | BCL2MCL1ALDH1A1PTPRCELANE | |
| SCHEMBL28641666 | 0.77 | S100A4 (0.40) | S100A4TRPV1BCL2MCL1ALDH1A1 | |
| Nobilone SCHEMBL30502482 | 0.76 | ESR1 (0.58) | ALDH1A1CYP1A2CYP3A4ESR1ESR2 | |
| SCHEMBL29664078 | 0.74 | S100A4 (0.80) | S100A4TRPV1BCL2MCL1ALDH1A1 | |
| SCHEMBL762135 | 0.74 | S100A4 (0.80) | S100A4TRPV1BCL2MCL1ALDH1A1 | |
| SCHEMBL29390614 | 0.74 | S100A4 (0.90) | S100A4TRPV1BCL2MCL1CYP1A2 | |
| SCHEMBL39700 | 0.74 | S100A4 (0.90) | S100A4TRPV1BCL2MCL1CYP1A2 | |
| SCHEMBL3717374 | 0.74 | S100A4 (0.80) | S100A4TRPV1BCL2MCL1ALDH1A1 | |
| SCHEMBL9642629 | 0.74 | PTPRC (0.62) | S100A4BCL2MCL1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113387779-A | Synthesis and preparation method of fluorenyl compound with 4-position substituent | 南京工业大学 | 2021-09-14 | — | — | CN | disclosed |