Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | THRA | P10827 | 4/20 | 0.33 |
| ▸ | THRB | P10828 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28641667 | 0.85 | GAA (0.33) | NPC1ALDH1A1GAARAB9A | |
| SCHEMBL28646147 | 0.80 | S100A4 (0.36) | PTPN1ALDH1A1GAA | |
| SCHEMBL5181645 | 0.68 | RARB (0.33) | PTPN1MAPT | |
| SCHEMBL6474422 | 0.66 | SMN1; SMN2 (0.48) | CYSLTR2CYSLTR1MAPTTHRATHRB | |
| SCHEMBL28639280 | 0.64 | MAPT (0.43) | PTPN1CYSLTR2CYSLTR1MAPTTHRA | |
| SCHEMBL15025770 | 0.63 | SMN1; SMN2 (0.51) | CYSLTR2CYSLTR1MAPTTHRATHRB | |
| SCHEMBL11061911 | 0.63 | PTPRC (0.51) | PTPN1MAPTTHRATHRBMEN1 | |
| SCHEMBL197409 | 0.63 | CA1 (0.41) | CYSLTR2CYSLTR1MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL197895 | 0.63 | CA1 (0.41) | CYSLTR2CYSLTR1MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL8773161 | 0.62 | S100A4 (0.56) | MAPTMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113387779-A | Synthesis and preparation method of fluorenyl compound with 4-position substituent | 南京工业大学 | 2021-09-14 | — | — | CN | disclosed |