Methacrylic Acid

Methacrylic Acid

SCHEMBL28639504

C=C(C)C(=O)O.C[N+](C)(C)CC(CCO)OP(=O)(O)O

nearest known ligand 0.36

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
CYP1A2 P05177 4/20 0.33
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
HRH1 P35367 1/20 0.33
PTPN1 P18031 1/20 0.32
SMPD1 P17405 3/20 0.32
MAPK1 P28482 4/20 0.31
MAPT P10636 4/20 0.31
GMNN O75496 3/20 0.31
NPSR1 Q6W5P4 3/20 0.31
BLM P54132 3/20 0.31
TSHR P16473 2/20 0.31
HSP90AA1 P07900 2/20 0.31
NR1H4 Q96RI1 2/20 0.31
TP53 P04637 1/20 0.31
CYP2C9 P11712 1/20 0.31
HIF1A Q16665 1/20 0.31
CHRM2 P08172 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL3884365 0.83 SMN1; SMN2 (0.36) LMNASMN1; SMN2CYP1A2MEN1KMT2A
SCHEMBL176508 0.78 THRB (0.38) LMNASMN1; SMN2CYP1A2MEN1KMT2A
SCHEMBL2319613 0.77 MEN1 (0.35) LMNASMN1; SMN2CYP1A2MEN1KMT2A
SCHEMBL541861 0.76 TSHR (0.42) LMNASMN1; SMN2CYP1A2MEN1KMT2A
SCHEMBL541372 0.75 TSHR (0.44) LMNASMN1; SMN2CYP1A2MEN1KMT2A
SCHEMBL14739090 0.74 MEN1 (0.35) LMNASMN1; SMN2CYP1A2MEN1KMT2A
SCHEMBL2944691 0.74 THRB (0.44) LMNASMN1; SMN2CYP1A2MEN1KMT2A
SCHEMBL28062034 0.74 TSHR (0.47) LMNASMN1; SMN2SMPD1NPSR1TSHR
SCHEMBL541808 0.74 TSHR (0.47) LMNASMN1; SMN2SMPD1NPSR1TSHR
SCHEMBL541106 0.74 TSHR (0.47) LMNASMN1; SMN2SMPD1NPSR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115192781-A Antimicrobial non-thrombogenic polymer compositions 路博润先进材料公司 2022-10-18 CN disclosed
CN-107787230-B Surface-modified polymer composition 路博润先进材料公司 2022-01-21 CN disclosed
CN-108366561-B Biocidal active polymer composition 路博润先进材料公司 2021-09-28 CN disclosed