Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 10/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL36451 | 0.95 | TSHR (0.53) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL23964584 | 0.95 | TSHR (0.53) | TSHRHPGDALDH1A1TP53HIF1A | |
| Methacrylic Acid SCHEMBL27888179 | 0.94 | TSHR (0.49) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL17947569 | 0.89 | TSHR (0.47) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL28111323 | 0.88 | TSHR (0.46) | TSHRHPGDALDH1A1TP53HIF1A | |
| Acrylic Acid SCHEMBL3180168 | 0.87 | TSHR (0.68) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL5606160 | 0.87 | TSHR (0.49) | TSHRHPGDALDH1A1TP53HIF1A | |
| Methacrylic Acid SCHEMBL27634098 | 0.86 | TSHR (0.55) | TSHRHPGDALDH1A1TP53HIF1A | |
| Acrylic Acid SCHEMBL6982262 | 0.85 | TSHR (0.50) | TSHRHPGDALDH1A1CYP3A4HSD17B10 | |
| Methacrylic Acid SCHEMBL28102391 | 0.85 | ALDH1A1 (0.38) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113396191-A | Curable composition for flexible hard coating | 日产化学株式会社 | 2021-09-14 | — | — | CN | disclosed |