SCHEMBL28639701

SCHEMBL28639701

CN(C(=O)c1ccc(S(C)(=O)=O)cc1)C1CCN(C(=O)OC(C)(C)C)CC1

nearest known ligand 0.75

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 19/20 0.75
USP30 Q70CQ3 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28628584 0.86 USP30 (0.67) GPR119USP30
SCHEMBL16999294 0.86 GPR119 (1.00) GPR119
SCHEMBL28632797 0.85 MEN1 (0.67) GPR119USP30
SCHEMBL9943184 0.84 USP30 (0.75) GPR119USP30
SCHEMBL17572993 0.84 USP30 (0.67) GPR119USP30
SCHEMBL28651615 0.84 GPR119 (0.74) GPR119USP30
SCHEMBL28651657 0.84 USP30 (0.64) GPR119USP30
SCHEMBL3036553 0.83 USP30 (0.64) GPR119USP30
SCHEMBL28634725 0.83 USP30 (0.61) GPR119USP30
SCHEMBL28292451 0.83 GPR119 (0.52) GPR119USP30

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109734700-B SMO inhibitor containing benzoyl piperidine structure and preparation method and application thereof 中国药科大学 2021-09-28 CN disclosed