Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | GPR119 | Q8TDV5 | 17/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28628584 | 0.85 | USP30 (0.67) | USP30GPR119 | |
| SCHEMBL27214747 | 0.85 | ALDH1A1 (0.56) | USP30ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL27178727 | 0.84 | ALDH1A1 (0.60) | USP30ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL28632797 | 0.84 | MEN1 (0.67) | USP30MEN1KMT2AGPR119 | |
| SCHEMBL9943184 | 0.83 | USP30 (0.75) | USP30MEN1KMT2AGPR119 | |
| SCHEMBL28639701 | 0.83 | GPR119 (0.75) | USP30GPR119 | |
| SCHEMBL28651657 | 0.83 | USP30 (0.64) | USP30MEN1KMT2AGPR119 | |
| SCHEMBL28651615 | 0.83 | GPR119 (0.74) | USP30ALDH1A1MEN1KMT2AGPR119 | |
| SCHEMBL17572993 | 0.83 | USP30 (0.67) | USP30GPR119 | |
| SCHEMBL3036553 | 0.82 | USP30 (0.64) | USP30MEN1KMT2AGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109734700-B | SMO inhibitor containing benzoyl piperidine structure and preparation method and application thereof | 中国药科大学 | 2021-09-28 | — | — | CN | disclosed |