Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | GPR183 | P32249 | 15/20 | 0.65 |
| ▸ | ACHE | P22303 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28640051 | 0.92 | ALDH1A1 (0.67) | KDM4EALDH1A1GPR183ACHEMEN1 | |
| SCHEMBL28637687 | 0.91 | KDM4E (0.66) | KDM4EALDH1A1GPR183MEN1KMT2A | |
| SCHEMBL28637002 | 0.91 | KDM4E (0.63) | KDM4EALDH1A1GPR183MEN1KMT2A | |
| SCHEMBL28651379 | 0.89 | ALDH1A1 (0.63) | KDM4EALDH1A1GPR183ACHEMEN1 | |
| SCHEMBL28641683 | 0.87 | KDM4E (0.65) | KDM4EALDH1A1GPR183MEN1KMT2A | |
| SCHEMBL28635282 | 0.86 | TDP1 (0.61) | KDM4EALDH1A1ACHEMEN1KMT2A | |
| SCHEMBL31533012 | 0.86 | GPR183 (0.73) | KDM4EALDH1A1GPR183ACHE | |
| SCHEMBL28632921 | 0.85 | KDM4E (0.56) | KDM4EALDH1A1GPR183MEN1KMT2A | |
| SCHEMBL28647986 | 0.84 | ACHE (0.76) | GPR183ACHE | |
| SCHEMBL28651404 | 0.83 | GPR183 (0.60) | KDM4EALDH1A1GPR183ACHEMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461639-B | Piperazine-containing ferulic acid derivative, and preparation method and application thereof | 贵州大学 | 2022-11-01 | — | — | CN | claimed |
| CN-113461639-A | Piperazine-containing ferulic acid derivative, and preparation method and application thereof | 贵州大学 | 2021-10-01 | — | — | CN | claimed |
| CN-113461639-B | Piperazine-containing ferulic acid derivative, and preparation method and application thereof | 贵州大学 | 2022-11-01 | — | — | CN | disclosed |
| CN-113461639-A | Piperazine-containing ferulic acid derivative, and preparation method and application thereof | 贵州大学 | 2021-10-01 | — | — | CN | disclosed |