Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2871579 | 0.91 | NPC1 (0.31) | NPC1MAPTRAB9ACA12CA1 | |
| Hydrochloric Acid SCHEMBL2862196 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL2856564 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL450509 | 0.83 | ALDH1A1 (0.32) | NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL2862334 | 0.82 | NPC1 (0.30) | NPC1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL5083491 | 0.81 | NPC1 (0.32) | NPC1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL2860070 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL5081233 | 0.78 | KCNK9 (0.31) | — | |
| Hydrochloric Acid SCHEMBL401301 | 0.77 | POLB (0.31) | — | |
| Hydrochloric Acid SCHEMBL8514188 | 0.76 | NPC1 (0.31) | NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1661921-B1 | Synthetic lubricating oil and lubricating oil composition thereof | MITSUI CHEMICALS INC (JP) | 2019-07-17 | — | — | EP | disclosed |
| US-7795194-B2 | Synthetic lubricating oil and lubricating oil composition | MITSUI CHEMICALS, INC. (JP) | 2010-09-14 | — | — | US | disclosed |
| US-20060116303-A1 | decene-ethylene copolymer, zirconium, titanium or hafnium fluorene-containing complexes, organometallics; improved high thermal oxidation stability, viscosity index, low-temperature viscosity properties and shear stability | MITSUI CHEMICALS, INC. (JP) | 2006-06-01 | — | — | US | disclosed |
| EP-1661921-A1 | Synthetic lubricating oil and lubricating oil composition thereof | Mitsui Chemicals, Inc. (JP) | 2006-05-31 | — | — | EP | disclosed |