Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22117724 | 1.00 | ALDH1A1 (0.35) | ALDH1A1POLBKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL22117720 | 1.00 | ALDH1A1 (0.35) | ALDH1A1POLBKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL22126916 | 0.82 | MEN1 (0.37) | ALDH1A1KMT2ACHRM1MEN1 | |
| SCHEMBL22126915 | 0.82 | MEN1 (0.37) | ALDH1A1KMT2ACHRM1MEN1 | |
| SCHEMBL19369518 | 0.82 | MEN1 (0.37) | ALDH1A1KMT2ACHRM1MEN1 | |
| SCHEMBL28646276 | 0.82 | MEN1 (0.37) | ALDH1A1KMT2ACHRM1MEN1 | |
| SCHEMBL29170241 | 0.78 | MGAM (0.36) | ALDH1A1POLBKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL29170244 | 0.78 | MGAM (0.36) | ALDH1A1POLBKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL29102591 | 0.78 | — | — | |
| SCHEMBL29102592 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113473987-A | Substituted 3- ((3-aminophenyl) amino) piperidine-2, 6-dione compounds, compositions thereof, and methods of treatment using the same | 细胞基因公司 | 2021-10-01 | — | — | CN | disclosed |