Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.31 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.31 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29170241 | 1.00 | MGAM (0.36) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL17317783 | 0.82 | POLB (0.37) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL30199413 | 0.80 | CHRM2 (0.41) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL29170220 | 0.80 | CHRM2 (0.41) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL29170218 | 0.80 | CHRM2 (0.41) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL28640464 | 0.78 | ALDH1A1 (0.35) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL22117724 | 0.78 | ALDH1A1 (0.35) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL22117720 | 0.78 | ALDH1A1 (0.35) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL15369661 | 0.78 | MGAM (0.44) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL21997783 | 0.78 | KMT2A (0.37) | MGAMGAASIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117715903-A | Cereblon binding compounds, compositions thereof, and methods for their use in therapy | 新基公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-117561249-A | Cereblon binding compounds, compositions thereof, and methods for their use in therapy | 细胞基因公司 | 2024-02-13 | — | — | CN | disclosed |