Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKACA | P17612 | 1/20 | 0.44 |
| ▸ | PRKACG | P22612 | 1/20 | 0.44 |
| ▸ | PRKACB | P22694 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11632146 | 0.83 | PRKACA (0.52) | PRKACAPRKACGPRKACBHTR1ADRD2 | |
| SCHEMBL28771523 | 0.81 | PRKACA (0.49) | PRKACAPRKACGPRKACBHTR1ADRD2 | |
| SCHEMBL2787499 | 0.81 | HTR1A (0.47) | HTR1ADRD2DRD3 | |
| SCHEMBL11635697 | 0.78 | — | — | |
| SCHEMBL138439 | 0.77 | PRKACA (0.50) | PRKACAPRKACGPRKACBHTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL12804515 | 0.75 | PRKACA (0.49) | PRKACAPRKACGPRKACBHTR1ADRD2 | |
| SCHEMBL28403744 | 0.75 | HTR1A (0.43) | HTR1ADRD2DRD3 | |
| SCHEMBL11632150 | 0.75 | PRKACA (0.55) | PRKACAPRKACGPRKACBHTR1ADRD2 | |
| SCHEMBL1637872 | 0.73 | HTR1A (0.46) | HTR1ADRD2DRD3 | |
| SCHEMBL11630650 | 0.72 | ALDH1A1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109879827-B | Indazole derivative and application thereof | 陕西理工大学 | 2022-05-31 | — | — | CN | disclosed |
| CN-108558763-B | Indazole-containing chalcone derivative and application thereof | 辽宁大学 | 2021-08-24 | — | — | CN | disclosed |
| CN-109879827-A | A kind of novel indazole analog derivative and its application | 陕西理工大学 | 2019-06-14 | — | — | CN | disclosed |