Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Tyrosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | NPY4R | P50391 | 5/20 | 0.38 |
| ▸ | NPY1R | P25929 | 4/20 | 0.38 |
| ▸ | NPY2R | P49146 | 4/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | NTSR2 | O95665 | 2/20 | 0.35 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.35 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.35 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.34 |
| ▸ | GSR | P00390 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tyrosine SCHEMBL28815050 | 0.93 | SLC7A5 (0.39) | SLC7A5THRBNPY4RNPY1RNPY2R | |
| Tyrosine SCHEMBL11404585 | 0.85 | SLC7A5 (0.57) | SLC7A5THRBITGB3ITGA2BLNPEP | |
| Tyrosine SCHEMBL6141122 | 0.85 | THRB (0.43) | SLC7A5THRBNPY4RNPY1RNPY2R | |
| Tyrosine SCHEMBL1931272 | 0.85 | THRB (0.43) | SLC7A5THRBNPY4RNPY1RNPY2R | |
| Tyrosine SCHEMBL27860049 | 0.85 | SLC7A5 (0.47) | SLC7A5THRBNPY4RNPY1RNPY2R | |
| Tyrosine SCHEMBL4586603 | 0.83 | SLC7A5 (0.60) | SLC7A5THRBNPY4RNPY1RNPY2R | |
| Tyrosine SCHEMBL28875441 | 0.83 | SLC7A5 (0.60) | SLC7A5THRBITGB3ITGA2BLNPEP | |
| Tyrosine SCHEMBL28676897 | 0.83 | SLC7A5 (0.60) | SLC7A5THRBITGB3ITGA2BLNPEP | |
| Tyrosine SCHEMBL28409961 | 0.81 | SLC7A5 (0.52) | SLC7A5THRBITGB3ITGA2BLNPEP | |
| Tyrosine SCHEMBL9111486 | 0.80 | THRB (0.37) | SLC7A5THRBNPY4RNPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112661814-A | Antibacterial peptide compound and antibacterial peptide extract as well as preparation method and application thereof | 华北制药集团新药研究开发有限责任公司 | 2021-04-16 | — | — | CN | disclosed |