Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 1.00 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | METAP2 | P50579 | 2/20 | 0.53 |
| ▸ | ALPL | P05186 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14027548 | 0.84 | RECQL (0.72) | RECQLRAB9ATP53NPC1MAPT | |
| SCHEMBL28631726 | 0.84 | RECQL (0.72) | RECQLRAB9ATP53NPC1MAPT | |
| SCHEMBL6207563 | 0.83 | RECQL (0.71) | RECQLRAB9ATP53NPC1SMN1; SMN2 | |
| SCHEMBL28631728 | 0.78 | SMN1; SMN2 (0.68) | RECQLTP53GAAMAPTSMN1; SMN2 | |
| SCHEMBL30939047 | 0.77 | MEN1 (0.71) | RECQLRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL14027549 | 0.73 | SMN1; SMN2 (0.63) | RECQLTP53GAAMAPTSMN1; SMN2 | |
| SCHEMBL28629734 | 0.73 | NPC1 (0.57) | RECQLRAB9ATP53NPC1SMN1; SMN2 | |
| SCHEMBL12090278 | 0.73 | RAB9A (0.62) | RECQLRAB9AGAAMAPTLMNA | |
| SCHEMBL13870209 | 0.70 | RECQL (0.54) | RECQLRAB9AGAANPC1MAPT | |
| SCHEMBL14049993 | 0.70 | RECQL (0.53) | RECQLRAB9ATP53SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110615792-B | 2-benzylthio-5-methyl-4, 7-dihydro- [1,2,4] triazolo [1,5-a ] pyrimidine derivatives | HEBEI UNIVERSITY OF TECHNOLOGY (CN) | 2021-08-31 | — | — | CN | claimed |
| CN-110615792-A | 2-benzylthio-5-methyl-4, 7-dihydro- [1,2,4] triazolo [1,5-a ] pyrimidine derivatives | 河北工业大学 | 2019-12-27 | — | — | CN | claimed |
| CN-110615792-B | 2-benzylthio-5-methyl-4, 7-dihydro- [1,2,4] triazolo [1,5-a ] pyrimidine derivatives | HEBEI UNIVERSITY OF TECHNOLOGY (CN) | 2021-08-31 | — | — | CN | disclosed |
| CN-110615792-A | 2-benzylthio-5-methyl-4, 7-dihydro- [1,2,4] triazolo [1,5-a ] pyrimidine derivatives | 河北工业大学 | 2019-12-27 | — | — | CN | disclosed |