SCHEMBL28640906

SCHEMBL28640906

[SiH3]O[SiH2]O[SiH2]Nc1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
TDP1 Q9NUW8 3/20 0.33
ALDH1A1 P00352 2/20 0.33
HSD17B10 Q99714 2/20 0.33
CTSD P07339 1/20 0.33
PTGS2 P35354 2/20 0.32
ALOX15 P16050 1/20 0.32
ALOX12 P18054 1/20 0.32
PTGS1 P23219 1/20 0.32
SLC6A2 P23975 1/20 0.32
MAPK1 P28482 1/20 0.32
HTR2B P41595 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
IDO1 P14902 2/20 0.31
LMNA P02545 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9324264 0.82 TSHR (0.42) TSHRTDP1ALDH1A1HSD17B10CTSD
SCHEMBL19973281 0.72 ALDH1A1 (0.40) ALDH1A1HSD17B10ALOX15ALOX12SLC6A2
SCHEMBL19973224 0.71 IDO1 (0.38) TDP1ALDH1A1ALOX12IDO1CYP3A4
Biphenyl SCHEMBL27732120 0.70 ALDH1A1 (0.47) TDP1ALDH1A1HSD17B10MAPK1IDO1
SCHEMBL2153932 0.67
SCHEMBL17046019 0.64
SCHEMBL28464256 0.64 ALDH1A1 (0.38) TSHRTDP1ALDH1A1HSD17B10CTSD
SCHEMBL2153175 0.64
SCHEMBL29262755 0.64
Biphenyl SCHEMBL5194632 0.64 ALDH1A1 (0.39) TDP1ALDH1A1HSD17B10MAPK1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113403605-A Compositions and methods for depositing silicon oxide films 弗萨姆材料美国有限责任公司 2021-09-17 CN claimed
CN-113403605-A Compositions and methods for depositing silicon oxide films 弗萨姆材料美国有限责任公司 2021-09-17 CN disclosed