Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 7/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28638488 | 0.94 | PSMB5 (0.41) | RORCPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL28638477 | 0.90 | KCNJ5 (0.47) | RORCRETWNT3ATRPV1KCNJ5 | |
| SCHEMBL28645373 | 0.90 | KCNJ5 (0.47) | RORCRETWNT3ATRPV1KCNJ5 | |
| SCHEMBL19205562 | 0.86 | RORC (0.41) | RORCPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL21796355 | 0.86 | RORC (0.41) | RORCPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL19205697 | 0.83 | KCNJ5 (0.48) | RORCRAB9AWNT3ATRPV1NPC1 | |
| SCHEMBL18448570 | 0.82 | CACNA1I (0.38) | RORCPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL18448919 | 0.81 | MAPT (0.38) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL21796367 | 0.81 | PSEN1 (0.39) | RORCPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL19205660 | 0.81 | PSEN1 (0.39) | RORCPSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026050-B | Novel compounds as ROR gamma modulators | 格兰马克药品股份有限公司 | 2021-04-30 | — | — | CN | claimed |