Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 15/20 | 0.60 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31053128 | 0.78 | BACE1 (0.61) | MAOB | |
| SCHEMBL1646385 | 0.78 | BACE1 (0.61) | MAOB | |
| SCHEMBL4883605 | 0.78 | BACE1 (0.53) | MAOB | |
| SCHEMBL27684770 | 0.76 | BACE1 (0.52) | MAOB | |
| SCHEMBL12767065 | 0.75 | ERN1 (1.00) | ERN1 | |
| SCHEMBL29635925 | 0.75 | KDM4E (0.61) | ERN1CRHBPCRHR2 | |
| SCHEMBL25962627 | 0.75 | KDM4E (0.61) | ERN1CRHBPCRHR2 | |
| SCHEMBL30683152 | 0.75 | ERN1 (0.73) | ERN1 | |
| SCHEMBL2817506 | 0.74 | CYP1A2 (0.51) | — | |
| SCHEMBL3235424 | 0.73 | BACE1 (0.59) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113493433-B | Benzopyrone derivative capable of serving as GPR35 receptor agonist, preparation method and application thereof | 泰州医药城国科化物生物医药科技有限公司 | 2023-12-01 | — | — | CN | disclosed |
| CN-113493433-A | Benzopyrone derivative capable of being used as GPR35 receptor agonist, preparation method and application thereof | 泰州医药城国科化物生物医药科技有限公司 | 2021-10-12 | — | — | CN | disclosed |