Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 3/20 | 0.55 |
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | TLR4 | O00206 | 1/20 | 0.53 |
| ▸ | TLR2 | O60603 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | CTSV | O60911 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | CDK4 | P11802 | 1/20 | 0.47 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.47 |
| ▸ | CCND1 | P24385 | 1/20 | 0.47 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31053128 | 1.00 | BACE1 (0.61) | BACE1MAOBMAOATLR4TLR2 | |
| SCHEMBL4883605 | 0.89 | BACE1 (0.53) | BACE1MAOBMAOATLR4TLR2 | |
| SCHEMBL6372335 | 0.88 | BACE1 (0.60) | BACE1MAOBMAOATLR4TLR2 | |
| SCHEMBL1646241 | 0.86 | NPC1 (0.58) | BACE1TLR4TLR2NPC1RAB9A | |
| SCHEMBL6927262 | 0.86 | MAOB (0.56) | BACE1MAOBMAOATLR4TLR2 | |
| SCHEMBL8943775 | 0.86 | MAOB (0.56) | BACE1MAOBMAOATLR4TLR2 | |
| SCHEMBL10909080 | 0.85 | MAOA (0.67) | BACE1MAOBMAOATLR4TLR2 | |
| SCHEMBL10909084 | 0.85 | MAOA (0.67) | BACE1MAOBMAOATLR4TLR2 | |
| SCHEMBL1645464 | 0.85 | RAB9A (0.49) | BACE1TLR4TLR2NPC1RAB9A | |
| SCHEMBL30832846 | 0.84 | MEN1 (0.57) | BACE1MAOBMAOATLR4TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12497386-B2 | Estrogen receptor-modulating compounds | RADIUS PHARMACEUTICALS, INC. (US) | 2025-12-16 | — | — | US | disclosed |
| US-20250340542-A1 | THYROID HORMONE RECEPTOR AGONISTS | INVENTISBIO CO LTD (CN) | 2025-11-06 | — | — | US | disclosed |
| EP-4635565-A1 | PRENYLATED TETRAHYDROQUINOLINES AND QUINOLINES WITH PPAR AGONIST ACTIVITY | Fundación para la Investigación del Hospital Clínico de la Comunidad Valenciana (INCLIVA) (ES) | 2025-10-22 | — | — | EP | disclosed |
| US-12391677-B2 | Thyroid hormone receptor agonists | InventisBio Co., Ltd. (CN) | 2025-08-19 | — | — | US | disclosed |
| US-20240308986-A1 | ESTROGEN RECEPTOR-MODULATING COMPOUNDS | RADIUS PHARMACEUTICALS, INC. | 2024-09-19 | — | — | US | disclosed |
| US-12018019-B2 | Estrogen receptor-modulating compounds | RADIUS PHARMACEUTICALS, INC. (US) | 2024-06-25 | — | — | US | disclosed |
| EP-3911660-B1 | PROCESS FOR PREPARATION OF 2-AMINO-5-HYDROXY PROPIOPHENONE | LAURUS LABS LTD (IN) | 2023-05-10 | — | — | EP | disclosed |
| US-20220332704-A1 | ESTROGEN RECEPTOR-MODULATING COMPOUNDS | RADIUS PHARMACEUTICALS, INC. | 2022-10-20 | — | — | US | disclosed |
| US-11434196-B2 | Process for preparation of 2-Amino-5-hydroxy propiophenone | LAURUS LABS LIMITED (IN) | 2022-09-06 | — | — | US | disclosed |
| US-11384068-B2 | Estrogen receptor-modulating compounds | RADIUS PHARMACEUTICALS, INC. (US) | 2022-07-12 | — | — | US | disclosed |
| US-6608049-B2 | Indazoles | BAYER AKTIENGESELLSCHAFT (DE) | 2003-08-19 | — | — | US | disclosed |
| EP-1324987-A1 | INDAZOLES WITH THYROID HORMON LIKE ACTIVITY, A PROCESS FOR ITS PREPARATION AND ITS USE IN PHARMACEUTICAL COMPOSITIONS | Bayer Aktiengesellschaft (DE) | 2003-07-09 | — | — | EP | disclosed |
| US-20020193610-A1 | Indazoles | BAYER AKTIENGESELLSCHAFT (DE) | 2002-12-19 | — | — | US | disclosed |
| US-20020173531-A1 | Indenoindolone compounds | LES LABORATOIRES SERVIER (FR) | 2002-11-21 | — | — | US | disclosed |
| EP-1245565-A1 | Indenoindolone derivatives, process for their preparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2002-10-02 | — | — | EP | disclosed |
| WO-2002022586-A1 | INDAZOLES HAVING AN ACTION SIMILAR TO THAT OF A THYROID HORMONE, METHOD FOR THE PRODUCTION THEREOF, AND THEIR USE IN MEDICAMENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-03-21 | — | — | WO | disclosed |
| EP-1107954-A1 | 2-OXO-$i(2H)-QUINOLINE DERIVATIVES | MERCK PATENT GmbH (DE) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012479-A1 | 2-OXO-2H-QUINOLINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-03-09 | — | — | WO | disclosed |
| EP-0008658-B1 | ALPHA-ETHINYL-ALPHA-AMINOACIDS AND THEIR ESTERS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1982-12-01 | — | — | EP | disclosed |
| EP-0008658-A1 | Alpha-ethinyl-alpha-aminoacids and their esters, and pharmaceutical compositions containing them | MERCK & CO. INC. (US) | 1980-03-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240308986-A1 | ESTROGEN RECEPTOR-MODULATING COMPOUNDS | ESR2, GPER1, ESR1 | BACE1 2861/4885MAOB 2697/4885MAOA 2604/4885 |
| US-20220332704-A1 | ESTROGEN RECEPTOR-MODULATING COMPOUNDS | ESR2, GPER1, ESR1 | BACE1 2861/4885MAOB 2697/4885MAOA 2604/4885 |
| US-12391677-B2 | Thyroid hormone receptor agonists | TSHR, THRA, TRHR | BACE1 4110/4885MAOB 3498/4885MAOA 3449/4885 |
| US-11384068-B2 | Estrogen receptor-modulating compounds | ESR2, GPER1, ESR1 | BACE1 2861/4885MAOB 2697/4885MAOA 2604/4885 |
| US-12018019-B2 | Estrogen receptor-modulating compounds | ESR2, GPER1, ESR1 | BACE1 2861/4885MAOB 2697/4885MAOA 2604/4885 |
| US-20250340542-A1 | THYROID HORMONE RECEPTOR AGONISTS | TSHR, THRA, TRHR | BACE1 3968/4885MAOB 3440/4885MAOA 3388/4885 |
| US-11434196-B2 | Process for preparation of 2-Amino-5-hydroxy propiophenone | DHPS, CYP3A5, CYP3A43 | BACE1 2730/4885MAOB 1929/4885MAOA 2589/4885 |
| US-20020193610-A1 | Indazoles | CYP3A43, CYP3A5, CYP3A4 | BACE1 787/4885MAOB 909/4885MAOA 722/4885 |
| US-12497386-B2 | Estrogen receptor-modulating compounds | ESR2, GPER1, ESR1 | BACE1 2861/4885MAOB 2697/4885MAOA 2604/4885 |
| US-20020173531-A1 | Indenoindolone compounds | MTNR1A, MTNR1B, CYP11B1 | BACE1 1616/4885MAOB 550/4885MAOA 535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.