SCHEMBL2864256

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2857478	0.85	MAP2K4 (0.52)	MAP2K4MAPK1PIM1MAPK3MAP4K1
	SCHEMBL31172491	0.84	ITK (0.46)	MAP2K4MAPK1MAPK6MAPKAPK3CSNK2A2
	SCHEMBL16981785	0.84	MAP2K4 (0.63)	MAP2K4MAPK1MAPK6MAPKAPK3ITK
	SCHEMBL2866791	0.83	MAP2K4 (0.69)	MAP2K4MAPK1MAPK6MAPKAPK3ITK
	SCHEMBL6502471	0.82	MAPK1 (0.55)	MAPK1MAPK3MAP4K1
	SCHEMBL2868586	0.81	MAPK1 (0.51)	MAP2K4MAPK1MAPK6MAPKAPK3ITK
	SCHEMBL2862381	0.79	MAP2K4 (0.70)	MAP2K4MAPK1MAPK6MAPKAPK3CSNK2A2
	SCHEMBL7092987	0.79	FFAR1 (0.58)	MAPK1PIM1MAPK3
	SCHEMBL2858476	0.78	MAP2K4 (0.68)	MAP2K4MAPK1MAPK6MAPKAPK3CSNK2A2
	SCHEMBL2864569	0.78	MAP2K4 (0.52)	MAP2K4MAPK1MAPK6MAPKAPK3ITK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.