SCHEMBL2864569

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2857271	0.86	MAPK1 (0.46)	MAP2K4MAPK1MAPK3HDAC6FLT3
	SCHEMBL2866791	0.80	MAP2K4 (0.69)	MAP2K4MAPK1MAPKAPK3MAPK6ITK
	SCHEMBL4903778	0.79	MAP2K4 (0.51)	MAP2K4MAPK1MAPKAPK3MAPK6ITK
	SCHEMBL2864256	0.78	MAP2K4 (0.52)	MAP2K4MAPK1MAPKAPK3MAPK6ITK
	SCHEMBL2861551	0.77	L3MBTL1 (0.60)	MEN1NPC1RAB9AKMT2A
	SCHEMBL2867287	0.77	MAP2K4 (0.51)	MAP2K4MAPK1MAPKAPK3MAPK6ITK
	SCHEMBL2867324	0.77	PIM1 (0.56)	MAP2K4MAPK1MAPKAPK3MAPK6ITK
	SCHEMBL2861172	0.76	LRRK2 (0.61)	MAP2K4MAPK1MAPKAPK3MAPK6ITK
	SCHEMBL4895080	0.76	ITK (0.54)	MAPK1ITKTGFBR1MAPK14NPC1
	SCHEMBL27558623	0.76	TTK (0.43)	MAPK1TGFBR1MAPK14NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.