SCHEMBL2864266

SCHEMBL2864266

CCCCOc1cc2c3cc(OCCCC)c(OCCCC)cc3c3cc(SCCCCCCCCCCCCCCCCCC[Si](OCC)(OCC)OCC)c(OCCCC)cc3c2cc1OCCCC

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CNR2 P34972 1/20 0.35
▸ LMNA P02545 3/20 0.34
▸ HTT P42858 2/20 0.34
▸ NPC1 O15118 1/20 0.34
▸ PKM P14618 1/20 0.34
▸ RAB9A P51151 1/20 0.34
▸ PTGS2 P35354 4/20 0.33
▸ PDE3B Q13370 1/20 0.32
▸ PDE3A Q14432 1/20 0.32
▸ NPSR1 Q6W5P4 2/20 0.31
▸ MAPT P10636 2/20 0.31
▸ NSD2 O96028 1/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ GAA P10253 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ TDP1 Q9NUW8 1/20 0.31
▸ L3MBTL1 Q9Y468 1/20 0.31
▸ EGFR P00533 1/20 0.31
▸ CYP1A2 P05177 2/20 0.30
▸ CYP2E1 P05181 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2860136 0.96 CNR2 (0.39) CNR2LMNAHTTNPC1PKM
SCHEMBL2852351 0.94 CNR2 (0.39) CNR2LMNAHTTNPC1PKM
SCHEMBL2858934 0.92 CNR2 (0.35) CNR2LMNAHTTNPC1PKM
SCHEMBL2860211 0.91 PDE3B (0.36) CNR2LMNAHTTNPC1PKM
SCHEMBL2852410 0.87 PDE3B (0.36) PDE3BPDE3AEGFRCYP1A2CYP2C9
SCHEMBL2863459 0.87 CNR2 (0.38) CNR2LMNAHTTPTGS2NPSR1
SCHEMBL2859062 0.87 LMNA (0.36) CNR2LMNAHTTNPC1PKM
SCHEMBL2866418 0.85 CNR2 (0.38) CNR2LMNAHTTPTGS2NPSR1
SCHEMBL2852404 0.84 PTGS2 (0.38) PTGS2CYP1A2CYP2E1CYP3A4CYP2C8
SCHEMBL2866298 0.84 TLR8 (0.38) LMNAMAPTMEN1KMT2AEGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7758932-B2 Liquid crystal display device and display apparatus RICOH COMPANY, LTD. (JP) 2010-07-20 — — US disclosed
US-20080305280-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY APPARATUS RICOH COMPANY, LTD. 2008-12-11 — — US disclosed
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