SCHEMBL2864321

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2868575	0.87	POLB (0.45)	POLBRAB9ANPC1SMN1; SMN2L3MBTL1
	SCHEMBL2860243	0.84	TTK (0.50)	POLBRAB9ANPC1SMN1; SMN2L3MBTL1
	SCHEMBL2867285	0.79	ITK (0.45)	RAB9ANPC1TTK
	SCHEMBL2868892	0.79	KMT2A (0.48)	POLBRAB9ANPC1SMN1; SMN2TDP1
	SCHEMBL4338506	0.76	GSK3B (0.50)	WNT1
	SCHEMBL2864448	0.74	MAPK1 (0.47)	ROCK1ROCK2WNT1TDP1TTK
	SCHEMBL2857629	0.71	MAP2K4 (0.46)	SMN1; SMN2ROCK1ROCK2
	SCHEMBL2863645	0.71	TTK (0.56)	POLBRAB9ANPC1SMN1; SMN2L3MBTL1
	SCHEMBL4335337	0.71	MAPK10 (0.52)	—
	SCHEMBL4331235	0.71	MEN1 (0.46)	POLBSMN1; SMN2ROCK1ROCK2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.