SCHEMBL2868575

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2868892	0.92	KMT2A (0.48)	POLBTTKWNT3ARAB9ANPC1
	SCHEMBL2864321	0.87	POLB (0.46)	POLBTTKRAB9ANPC1TDP1
	SCHEMBL2863645	0.84	TTK (0.56)	POLBTTKRAB9ANPC1KMT2A
	SCHEMBL2863255	0.78	TTK (0.47)	TTKSMN1; SMN2PLK4
	SCHEMBL2864566	0.76	TTK (0.55)	POLBTTKRAB9ANPC1TDP1
	SCHEMBL6545461	0.72	ICMT (0.45)	CCNA2CDK2CCNA1
	SCHEMBL2571823	0.72	TTK (0.78)	TTKPLK4
	SCHEMBL2870906	0.71	TTK (0.72)	TTKCLK2CLK3DYRK1A
	SCHEMBL2860243	0.71	TTK (0.50)	POLBTTKRAB9ANPC1KMT2A
	SCHEMBL5379411	0.71	TTK (0.52)	TTKRAB9ANPC1TDP1PLK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.