SCHEMBL2863645

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2864566	0.91	TTK (0.55)	TTKPOLBMEN1KMT2ARAB9A
	SCHEMBL2860243	0.87	TTK (0.50)	TTKPOLBMEN1KMT2ARAB9A
	SCHEMBL2861303	0.85	TTK (0.75)	TTKPOLBMEN1KMT2ARAB9A
	SCHEMBL2868575	0.84	POLB (0.45)	TTKPOLBKMT2ARAB9ASMN1; SMN2
	SCHEMBL2863255	0.79	TTK (0.47)	TTKSMN1; SMN2MAPT
	SCHEMBL4334573	0.79	TTK (0.55)	TTKPOLBRAB9AMAPK1KDM4E
	SCHEMBL4148920	0.76	TTK (0.53)	TTKPOLBMEN1KMT2ARAB9A
	SCHEMBL2868892	0.76	KMT2A (0.48)	TTKPOLBMEN1KMT2ARAB9A
	SCHEMBL2855841	0.75	TTK (0.52)	TTKPOLBMEN1KMT2AKDM4E
	SCHEMBL4334969	0.72	TTK (0.54)	TTKPOLBMEN1KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.