SCHEMBL28643239

SCHEMBL28643239

COc1cccc(OC)c1OC.c1cncc(-c2cccnc2-c2cccnc2)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FYN P06241 1/20 0.52
PTGS2 P35354 1/20 0.51
CYP2A6 P11509 1/20 0.49
POLB P06746 3/20 0.48
MAPK1 P28482 1/20 0.48
HTT P42858 1/20 0.48
CYP11B1 P15538 2/20 0.46
CYP11B2 P19099 2/20 0.46
CYP17A1 P05093 1/20 0.46
CYP19A1 P11511 1/20 0.46
EPHB4 P54760 1/20 0.46
P2RX7 Q99572 1/20 0.46
ABCB1 P08183 1/20 0.46
ABCC1 P33527 1/20 0.46
PRKD3 O94806 1/20 0.45
PRKCG P05129 1/20 0.45
PRKCB P05771 1/20 0.45
LCK P06239 1/20 0.45
PRKCA P17252 1/20 0.45
PRKCH P24723 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5457794 0.85 POLB (0.55) FYNPOLBMAPK1HTTCYP11B1
SCHEMBL16026628 0.83 PTGS2 (0.62) PTGS2CYP2A6HTTCYP11B1CYP11B2
SCHEMBL30199921 0.82 CYP2A6 (0.61) PTGS2CYP2A6POLBMAPK1HTT
SCHEMBL4881988 0.82 CYP2A6 (0.61) PTGS2CYP2A6POLBMAPK1HTT
Ethane SCHEMBL28235431 0.82 PTGS2 (0.65) PTGS2CYP2A6HTTCYP11B1CYP11B2
SCHEMBL30032 0.82 PTGS2 (0.64) PTGS2CYP2A6HTTCYP11B1CYP11B2
SCHEMBL28181896 0.82 PTGS2 (0.64) PTGS2CYP2A6HTTCYP11B1CYP11B2
SCHEMBL31635952 0.82 PTGS2 (0.64) PTGS2CYP2A6HTTCYP11B1CYP11B2
SCHEMBL28395310 0.81 POLB (0.51) FYNPOLBMAPK1HTTCYP11B1
SCHEMBL12498499 0.81 CYP2A6 (0.51) CYP2A6POLBMAPK1HTTCYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113563389-B Tri-pyridyl cobalt organic complex, tri-pyridyl cobalt organic supramolecular hydrogel, and preparation method and application thereof 中南大学 2022-03-29 CN disclosed
CN-113563389-A Tri-pyridyl cobalt organic complex, tri-pyridyl cobalt organic supramolecular hydrogel, and preparation method and application thereof 中南大学 2021-10-29 CN disclosed