Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 9/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28643274 | 0.93 | RPS6KB1 (0.41) | CHRM3RPS6KB1 | |
| SCHEMBL2557591 | 0.85 | FFAR4 (0.41) | FFAR4RPS6KB1CHRM4 | |
| SCHEMBL28659709 | 0.82 | CHRM3 (0.34) | CHRM3 | |
| SCHEMBL22781025 | 0.82 | BPTF (0.48) | FFAR4CHRM4 | |
| SCHEMBL28647168 | 0.81 | MC4R (0.42) | HDAC3HDAC1HDAC2FFAR4CHRM3 | |
| SCHEMBL28919339 | 0.80 | CHRM4 (0.52) | RPS6KB1CHRM4MAPT | |
| SCHEMBL2560980 | 0.79 | ALDH1A1 (0.49) | MAPT | |
| SCHEMBL28642501 | 0.75 | CHRM3 (0.40) | CHRM3RPS6KB1 | |
| SCHEMBL28653059 | 0.75 | CHRM3 (0.40) | CHRM3RPS6KB1 | |
| SCHEMBL28464943 | 0.74 | ALDH1A1 (0.56) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113527298-A | Macrocyclic lactam derivative, preparation method and application thereof | 浙江海正药业股份有限公司 | 2021-10-22 | — | — | CN | disclosed |