Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 14/20 | 0.41 |
| ▸ | LPL | P06858 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | RBP4 | P02753 | 3/20 | 0.40 |
| ▸ | TTR | P02766 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28643265 | 0.93 | HDAC3 (0.39) | RPS6KB1CHRM3 | |
| SCHEMBL28653059 | 0.82 | CHRM3 (0.40) | RPS6KB1CHRM3LPLLIPGRBP4 | |
| SCHEMBL28642501 | 0.82 | CHRM3 (0.40) | RPS6KB1CHRM3LPLLIPGRBP4 | |
| SCHEMBL28647415 | 0.81 | RBP4 (0.38) | RPS6KB1CHRM3LPLLIPGRBP4 | |
| SCHEMBL28653069 | 0.81 | RBP4 (0.38) | RPS6KB1CHRM3LPLLIPGRBP4 | |
| SCHEMBL28647418 | 0.81 | RBP4 (0.38) | RPS6KB1CHRM3LPLLIPGRBP4 | |
| SCHEMBL28653070 | 0.81 | RBP4 (0.38) | RPS6KB1CHRM3LPLLIPGRBP4 | |
| SCHEMBL2557591 | 0.80 | FFAR4 (0.41) | RPS6KB1LPLLIPG | |
| SCHEMBL28659709 | 0.80 | CHRM3 (0.34) | CHRM3 | |
| SCHEMBL22781025 | 0.77 | BPTF (0.48) | LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113527298-A | Macrocyclic lactam derivative, preparation method and application thereof | 浙江海正药业股份有限公司 | 2021-10-22 | — | — | CN | disclosed |