Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 7/20 | 0.92 |
| ▸ | LPL | P06858 | 6/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | BID | P55957 | 3/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.44 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.44 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.44 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL747937 | 0.98 | LIPG (0.96) | LIPGLPLTRPV1MGLLALOX5 | |
| SCHEMBL29670235 | 0.98 | LIPG (0.96) | LIPGLPLTRPV1MGLLALOX5 | |
| SCHEMBL435360 | 0.96 | LIPG (1.00) | LIPGLPLTRPV1MGLLALOX5 | |
| SCHEMBL31591938 | 0.96 | LIPG (1.00) | LIPGLPLTRPV1MGLLALOX5 | |
| SCHEMBL29670093 | 0.96 | LIPG (1.00) | LIPGLPLTRPV1MGLLALOX5 | |
| SCHEMBL31403378 | 0.96 | LIPG (1.00) | LIPGLPLTRPV1MGLLALOX5 | |
| SCHEMBL4449189 | 0.96 | LIPG (1.00) | LIPGLPLTRPV1MGLLALOX5 | |
| SCHEMBL11415024 | 0.96 | LIPG (1.00) | LIPGLPLTRPV1MGLLALOX5 | |
| SCHEMBL6153283 | 0.96 | LIPG (1.00) | LIPGLPLTRPV1MGLLALOX5 | |
| SCHEMBL1128560 | 0.92 | LIPG (0.85) | LIPGLPLTRPV1MGLLALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113620901-B | Crown ether derived chiral 1,1 '-bi-2, 2' -naphthol, preparation method and application thereof | 杭州师范大学 | 2023-02-10 | — | — | CN | disclosed |
| CN-113620901-A | Crown ether derived chiral 1,1 '-bi-2, 2' -naphthol, preparation method and application thereof | 杭州师范大学 | 2021-11-09 | — | — | CN | disclosed |