Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 7/20 | 0.96 |
| ▸ | LPL | P06858 | 6/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | BID | P55957 | 3/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.45 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.45 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | EP300 | Q09472 | 1/20 | 0.45 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.45 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.45 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.45 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29670235 | 1.00 | LIPG (0.96) | LIPGLPLTRPV1MGLLALOX5 | |
| Methyl Alcohol SCHEMBL28643289 | 0.98 | LIPG (0.92) | LIPGLPLTRPV1MGLLALOX5 | |
| SCHEMBL31403378 | 0.98 | LIPG (1.00) | LIPGLPLTRPV1MGLLALOX5 | |
| SCHEMBL29670093 | 0.98 | LIPG (1.00) | LIPGLPLTRPV1MGLLALOX5 | |
| SCHEMBL6153283 | 0.98 | LIPG (1.00) | LIPGLPLTRPV1MGLLALOX5 | |
| SCHEMBL31591938 | 0.98 | LIPG (1.00) | LIPGLPLTRPV1MGLLALOX5 | |
| SCHEMBL435360 | 0.98 | LIPG (1.00) | LIPGLPLTRPV1MGLLALOX5 | |
| SCHEMBL11415024 | 0.98 | LIPG (1.00) | LIPGLPLTRPV1MGLLALOX5 | |
| SCHEMBL4449189 | 0.98 | LIPG (1.00) | LIPGLPLTRPV1MGLLALOX5 | |
| SCHEMBL1128560 | 0.94 | LIPG (0.85) | LIPGLPLTRPV1MGLLALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117865773-A | Preparation method of difluoromethyl aromatic compound based on palladium-catalyzed decarbonylation coupling | 大连理工大学 | 2024-04-12 | — | — | CN | claimed |
| CN-110041174-B | EBINOL axis chiral compound and synthetic method and application thereof | 南方科技大学 | 2022-04-12 | — | — | CN | claimed |
| CN-119569754-A | Thiophene pyrrole fused benzothiadiazole dichroic dye and application thereof | 西安工业大学 | 2025-03-07 | — | — | CN | disclosed |
| CN-118388973-A | Benzotriazole dichroic dye and application thereof | 西安近代化学研究所 | 2024-07-26 | — | — | CN | disclosed |
| CN-110041174-B | EBINOL axis chiral compound and synthetic method and application thereof | 南方科技大学 | 2022-04-12 | — | — | CN | disclosed |
| CN-113149839-B | Self-aligned liquid crystal medium compound and application thereof | 北京八亿时空液晶科技股份有限公司 | 2022-02-22 | — | — | CN | disclosed |
| CN-108753312-B | Liquid crystal compound, preparation method thereof, composition containing liquid crystal compound and high-frequency component containing liquid crystal medium | 西安近代化学研究所 | 2021-07-27 | — | — | CN | disclosed |
| CN-113149839-A | Self-aligned liquid crystal medium compound and application thereof | 北京八亿时空液晶科技股份有限公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-110746981-B | Liquid crystal composition and application thereof | 武汉轻工大学 | 2021-06-29 | — | — | CN | disclosed |
| CN-110760311-B | Lateral methyl poly-biphenyl liquid crystal compound, liquid crystal composition and application thereof | 武汉轻工大学 | 2021-06-29 | — | — | CN | disclosed |
| CN-108517217-B | Acetylene liquid crystal compound, preparation method thereof, composition containing acetylene liquid crystal compound and high-frequency component containing acetylene liquid crystal medium | 西安近代化学研究所 | 2020-02-14 | — | — | CN | disclosed |
| EP-1856090-A2 | SUBSTITUTED THIOPHENE DERIVATIVES AS GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006086488-A2 | SUBSTITUTED THIOPHENE DERIVATIVES AS GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2006-08-17 | — | — | WO | disclosed |
| US-20040158074-A1 | Substituted biphenyl compounds for the treatment of inflammation | G.D. SEARLE & CO. | 2004-08-12 | — | — | US | disclosed |
| US-6677488-B2 | AS AN EXAMPLE, 4-(4,5-DIFLUORO-2-(3-CHLORO-4-FLUOROPHENYL) PHENYLBENZENESULFONAMIDE; ANTIARTHRITIC AGENTS; ANTIPYRETICS; ANALGESICS; PROSTAGLANDIN INHIBITORS; SIDE EFFECT REDUCTION | G.D. SEARLE & CO. | 2004-01-13 | — | — | US | disclosed |
| US-20020169206-A1 | Substituted biphenyl compounds for the treatment of inflammation | G.D. SEARLE & CO. (US) | 2002-11-14 | — | — | US | disclosed |
| EP-0794942-B1 | SUBSTITUTED BIPHENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | SEARLE & CO (US) | 2000-05-31 | — | — | EP | disclosed |
| US-5739166-A | ALKYLSULFONYL OR AMINOSULFONYL SUBSTITUTED AROMATIC COMPOUNDS AS NON-STEROIDAL ANTIINFLAMMATORY AGENT | G.D. SEARLE & CO. (US) | 1998-04-14 | — | — | US | disclosed |
| EP-0794942-A1 | SUBSTITUTED BIPHENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1997-09-17 | — | — | EP | disclosed |
| WO-1996016934-A1 | SUBSTITUTED BIPHENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-06-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020169206-A1 | Substituted biphenyl compounds for the treatment of inflammation | AHR, ARNT, GPBAR1 | LIPG 628/4885LPL 501/4885TRPV1 917/4885 |
| US-20040158074-A1 | Substituted biphenyl compounds for the treatment of inflammation | AHR, ARNT, GPBAR1 | LIPG 628/4885LPL 501/4885TRPV1 917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.