Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.37 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28648395 | 0.85 | L3MBTL1 (0.49) | TAS1R3TAS1R1L3MBTL1HDAC2CYP2C9 | |
| SCHEMBL2487219 | 0.85 | TAS1R3 (0.48) | TAS1R3TAS1R1L3MBTL1HDAC2CYP2C9 | |
| SCHEMBL13913176 | 0.85 | TAS1R3 (0.48) | TAS1R3TAS1R1L3MBTL1HDAC2CYP2C9 | |
| SCHEMBL2487959 | 0.85 | TAS1R3 (0.48) | TAS1R3TAS1R1L3MBTL1HDAC2CYP2C9 | |
| SCHEMBL711890 | 0.82 | TAS1R3 (0.46) | TAS1R3TAS1R1L3MBTL1HDAC2CYP2C9 | |
| SCHEMBL3241409 | 0.82 | TAS1R3 (0.46) | TAS1R3TAS1R1L3MBTL1HDAC2CYP2C9 | |
| SCHEMBL28790681 | 0.82 | L3MBTL1 (0.54) | L3MBTL1HDAC2CYP2C9KMT2APOLB | |
| SCHEMBL28790680 | 0.82 | L3MBTL1 (0.54) | L3MBTL1HDAC2CYP2C9KMT2APOLB | |
| SCHEMBL15107352 | 0.81 | TAS1R3 (0.46) | TAS1R3TAS1R1L3MBTL1HDAC2CYP2C9 | |
| SCHEMBL10218991 | 0.81 | TAS1R3 (0.49) | TAS1R3TAS1R1L3MBTL1HDAC2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113582904-B | 5-n-propyl-4-hydroxypyrrole-2-ketone derivative and preparation method and application thereof | 安徽农业大学 | 2023-03-10 | — | — | CN | disclosed |
| CN-113582904-A | 5-n-propyl-4-hydroxypyrrole-2-ketone derivative and preparation method and application thereof | 安徽农业大学 | 2021-11-02 | — | — | CN | disclosed |