SCHEMBL28643773

SCHEMBL28643773

O=CN1CC=Cc2cnccc21

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14494876 0.75 GAA (0.34)
SCHEMBL5823517 0.72 KDM4E (0.32)
SCHEMBL31613275 0.70
SCHEMBL30986150 0.66 CHRM2 (0.41) CYP2A6
SCHEMBL15083805 0.65 P2RX4 (0.36)
SCHEMBL9934950 0.64 CYP2A6 (0.37) CYP2A6
SCHEMBL30986187 0.62 HTR2C (0.40) CYP2A6
SCHEMBL4780802 0.61 P2RX4 (0.37)
SCHEMBL27531300 0.60 MEN1 (0.31)
SCHEMBL28713089 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113633623-A Capsule containing naphthyridine compounds and preparation method thereof 石家庄四药有限公司 2021-11-12 CN claimed
CN-113520999-B Oral liquid containing naphthyridine compounds and preparation method thereof 石家庄四药有限公司 2022-08-09 CN disclosed
CN-113633623-A Capsule containing naphthyridine compounds and preparation method thereof 石家庄四药有限公司 2021-11-12 CN disclosed
CN-113633623-A Capsule containing naphthyridine compounds and preparation method thereof 石家庄四药有限公司 2021-11-12 CN disclosed
CN-113520999-A Oral liquid containing naphthyridine compounds and preparation method thereof 石家庄四药有限公司 2021-10-22 CN disclosed