SCHEMBL28644170

SCHEMBL28644170

[c]1cccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-c3ccccc3)n2)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.42
ADORA2A P29274 3/20 0.42
ADORA1 P30542 3/20 0.42
ADORA3 P0DMS8 2/20 0.42
ADORA2B P29275 2/20 0.42
ALOX15 P16050 2/20 0.42
GPR55 Q9Y2T6 1/20 0.42
L3MBTL1 Q9Y468 3/20 0.41
MAPT P10636 5/20 0.37
ALDH1A1 P00352 3/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
HTT P42858 2/20 0.37
POLB P06746 3/20 0.37
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
HPGD P15428 1/20 0.36
ABCG2 Q9UNQ0 1/20 0.36
MAPK1 P28482 4/20 0.34
RAB9A P51151 3/20 0.34
NPC1 O15118 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28663752 0.89 L3MBTL1 (0.50) TSHRADORA2AADORA1ADORA3ADORA2B
SCHEMBL9957274 0.85 MAOB (0.39) TSHRADORA2AADORA1GPR55L3MBTL1
SCHEMBL28639710 0.84 ADORA2A (0.46) TSHRADORA2AADORA1ADORA3ADORA2B
SCHEMBL21922946 0.83 L3MBTL1 (0.56) TSHRADORA2AADORA1ADORA3ADORA2B
SCHEMBL17720964 0.81 L3MBTL1 (0.54) TSHRADORA2AADORA1ADORA3ADORA2B
SCHEMBL1368412 0.81 ALDH1A1 (0.41) GPR55ALDH1A1HPGDABCG2MAPK1
SCHEMBL12854006 0.81 L3MBTL1 (0.54) TSHRADORA2AADORA1ADORA3ADORA2B
SCHEMBL24689432 0.79 L3MBTL1 (0.52) TSHRADORA2AADORA1ADORA3ADORA2B
SCHEMBL17720965 0.79 L3MBTL1 (0.52) TSHRADORA2AADORA1ADORA3ADORA2B
SCHEMBL31290117 0.79 L3MBTL1 (0.52) TSHRADORA2AADORA1ADORA3ADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113631556-A Compound, and organic semiconductor layer, organic electronic device, and display device or lighting device comprising same 诺瓦尔德股份有限公司 2021-11-09 CN disclosed
CN-113490672-A Compound and organic electronic device comprising the same 诺瓦尔德股份有限公司 2021-10-08 CN disclosed