Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 12/20 | 0.63 |
| ▸ | LOX | P28300 | 12/20 | 0.54 |
| ▸ | MAOA | P21397 | 5/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.41 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.41 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19274424 | 0.84 | LOX (0.50) | LOXL2LOXMAOA | |
| SCHEMBL19274258 | 0.83 | LOX (0.42) | LOXL2LOXMAOAKCNH2 | |
| SCHEMBL19274294 | 0.80 | LOX (0.53) | LOXL2LOXMAOA | |
| SCHEMBL28641800 | 0.80 | LOXL2 (0.64) | LOXL2LOXMAOAKCNH2LOXL3 | |
| SCHEMBL29970998 | 0.80 | LOXL2 (0.64) | LOXL2LOXMAOAKCNH2LOXL3 | |
| SCHEMBL29971595 | 0.80 | LOXL2 (0.62) | LOXL2LOXMAOAKCNH2LOXL3 | |
| SCHEMBL28657448 | 0.80 | LOXL2 (0.62) | LOXL2LOXMAOAKCNH2LOXL3 | |
| SCHEMBL19259978 | 0.79 | LOX (0.47) | LOXL2LOXMAOA | |
| SCHEMBL19274508 | 0.79 | LOX (0.47) | LOXL2LOXMAOA | |
| SCHEMBL21016658 | 0.78 | LOX (0.44) | LOXL2LOXMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311839-B | Methylamine derivatives as lysyl oxidase inhibitors for the treatment of cancer | 癌症研究协会皇家癌症医院 | 2021-11-02 | — | — | CN | disclosed |