Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28644673 | 1.00 | ALDH1A1 (0.46) | ALDH1A1TSHRNPSR1MAPTTDP1 | |
| SCHEMBL28663249 | 0.92 | NPSR1 (0.45) | ALDH1A1TSHRNPSR1MAPTTDP1 | |
| SCHEMBL16504878 | 0.84 | MEN1 (0.46) | ALDH1A1TSHRNPSR1TDP1HDAC4 | |
| SCHEMBL16504877 | 0.84 | MEN1 (0.46) | ALDH1A1TSHRNPSR1TDP1HDAC4 | |
| SCHEMBL21372526 | 0.84 | MEN1 (0.46) | ALDH1A1TSHRNPSR1TDP1HDAC4 | |
| SCHEMBL16504745 | 0.84 | MEN1 (0.46) | ALDH1A1TSHRNPSR1TDP1HDAC4 | |
| SCHEMBL15537106 | 0.84 | MEN1 (0.46) | ALDH1A1TSHRNPSR1TDP1HDAC4 | |
| SCHEMBL20122287 | 0.84 | MEN1 (0.46) | ALDH1A1TSHRNPSR1TDP1HDAC4 | |
| SCHEMBL13430793 | 0.81 | SIRT2 (0.52) | MAPTCTSKFOLH1 | |
| SCHEMBL22473734 | 0.80 | MEN1 (0.50) | ALDH1A1TSHRTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108794572-B | Total synthesis method of natural product Lucentamycin A | 上海交通大学 | 2021-10-15 | — | — | CN | disclosed |