Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.64 |
| ▸ | MAPT | P10636 | 8/20 | 0.64 |
| ▸ | NPC1 | O15118 | 7/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | TP53 | P04637 | 3/20 | 0.64 |
| ▸ | GLA | P06280 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8137580 | 0.89 | RAB9A (0.51) | RAB9ASMN1; SMN2MAPTNPC1HPGD | |
| SCHEMBL31650106 | 0.84 | HSP90AA1 (0.52) | RAB9ASMN1; SMN2MAPTNPC1HPGD | |
| SCHEMBL31650132 | 0.83 | MAPT (0.47) | RAB9ASMN1; SMN2MAPTNPC1HPGD | |
| SCHEMBL31650451 | 0.82 | SMN1; SMN2 (0.58) | RAB9ASMN1; SMN2MAPTNPC1HPGD | |
| SCHEMBL25170969 | 0.82 | TDP2 (0.57) | RAB9ASMN1; SMN2MAPTNPC1HPGD | |
| SCHEMBL31016026 | 0.82 | TDP2 (0.57) | RAB9ASMN1; SMN2MAPTNPC1HPGD | |
| SCHEMBL31650221 | 0.80 | RAB9A (0.46) | RAB9ASMN1; SMN2MAPTNPC1HPGD | |
| SCHEMBL11902861 | 0.80 | RAB9A (0.64) | RAB9ASMN1; SMN2MAPTNPC1HPGD | |
| SCHEMBL29683123 | 0.80 | RAB9A (0.64) | RAB9ASMN1; SMN2MAPTNPC1HPGD | |
| SCHEMBL31650057 | 0.79 | RAB9A (0.63) | RAB9ASMN1; SMN2MAPTNPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025136811-A1 | CHEMICAL COMPOUNDS AND USES THEREOF | IDEAYA BIOSCIENCES, INC. (US) | 2025-06-26 | — | — | WO | disclosed |
| CN-111454229-B | Dihydronaphthoisoxazole derivative and application thereof in antitumor drugs | 徐瑛 | 2022-07-19 | — | — | CN | disclosed |
| CN-113416171-A | 4, 5-dihydronaphthoisoxazole derivatives and application thereof in antitumor drugs | 守恒(厦门)医疗科技有限公司 | 2021-09-21 | — | — | CN | disclosed |
| CN-113292554-A | Dihydronaphtho [2,1-d ] isoxazole amide derivatives and application thereof in antitumor drugs | 守恒(厦门)医疗科技有限公司 | 2021-08-24 | — | — | CN | disclosed |