SCHEMBL28645290

SCHEMBL28645290

CCN(C)C=Nc1c(C)cc(OC)cc1Nc1ccc(OC)c(F)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GALR2 O43603 5/20 0.41
TUBB1 Q9H4B7 4/20 0.36
TUBB4A P04350 1/20 0.36
TUBB P07437 1/20 0.36
TUBA3C P0DPH7 1/20 0.36
TUBA1B P68363 1/20 0.36
TUBA4A P68366 1/20 0.36
TUBB4B P68371 1/20 0.36
TUBB3 Q13509 1/20 0.36
TUBB2A Q13885 1/20 0.36
TUBB8 Q3ZCM7 1/20 0.36
TUBA3E Q6PEY2 1/20 0.36
TUBA1A Q71U36 1/20 0.36
TUBA1C Q9BQE3 1/20 0.36
TUBB6 Q9BUF5 1/20 0.36
TUBB2B Q9BVA1 1/20 0.36
ABCG2 Q9UNQ0 2/20 0.34
ABCB1 P08183 1/20 0.34
ABCC1 P33527 1/20 0.34
GALR1 P47211 4/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28637700 0.89 GALR2 (0.37) GALR2TUBB1TUBB4ATUBBTUBA3C
SCHEMBL22231885 0.86 GALR2 (0.41) GALR2TUBB1TUBB4ATUBBTUBA3C
SCHEMBL22231883 0.86 GALR2 (0.41) GALR2TUBB1TUBB4ATUBBTUBA3C
SCHEMBL28642106 0.78 RAPGEF4 (0.38)
SCHEMBL22232249 0.78 GALR2 (0.38) GALR2TUBB1TUBB4ATUBBTUBA3C
SCHEMBL22232252 0.78 GALR2 (0.38) GALR2TUBB1TUBB4ATUBBTUBA3C
SCHEMBL22232031 0.78 KCNH2 (0.40) GALR2TUBB1TUBB4ATUBBTUBA3C
SCHEMBL22232172 0.78 GALR2 (0.39) GALR2TUBB1ABCG2ABCB1ABCC1
SCHEMBL22232170 0.78 GALR2 (0.39) GALR2TUBB1ABCG2ABCB1ABCC1
SCHEMBL22232034 0.78 KCNH2 (0.40) GALR2TUBB1TUBB4ATUBBTUBA3C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113454063-A 3-substituted phenylamidine compounds, preparation method and application thereof PI工业有限公司 2021-09-28 CN disclosed