Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 10/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19643345 | 0.82 | ADORA1 (0.42) | RBP4MAPK1 | |
| SCHEMBL17317850 | 0.79 | P2RX7 (0.39) | RBP4HCAR2KMT2AP2RX7MAPK1 | |
| SCHEMBL18587623 | 0.79 | RBP4 (0.39) | RBP4HCAR2KMT2ABRD4CREBBP | |
| SCHEMBL28646727 | 0.76 | P2RX7 (0.39) | RBP4HCAR2KMT2AP2RX7MAPK1 | |
| SCHEMBL28644919 | 0.76 | CREBBP (0.41) | RBP4P2RX7MAPK1BRD4CREBBP | |
| SCHEMBL28662073 | 0.75 | CREBBP (0.39) | RBP4HCAR2KMT2AP2RX7MAPK1 | |
| SCHEMBL21003205 | 0.73 | P2RX7 (0.38) | P2RX7 | |
| SCHEMBL5953472 | 0.73 | HCAR2 (0.56) | HCAR2KMT2AMAPK1TSHRBRD4 | |
| SCHEMBL23881426 | 0.72 | P2RX7 (0.37) | RBP4P2RX7MAPK1BRD4CREBBP | |
| SCHEMBL5644483 | 0.72 | DPP4 (0.50) | RBP4P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476663-B | Pyrazolopyridine derivatives for the treatment of cancer | 基因泰克公司 | 2021-11-09 | — | — | CN | disclosed |